Sina Witzel
C-H Activation in Gold-Catalyzed Photochemistry
S. Witzel1*, J. Xie2, A. S. K. Hashmi1
(1) Institute of Organic Chemistry, Heidelberg University, Im Neuenheimer Feld 270, 69120 Heidelberg, Germany
(2) School of Chemistry and Chemical Engineering, Nanjing University, Hankou Road 22, 210093 Nanjing, China
Visible light photoredox catalysis has recently experienced a revival and today functions as a versatile tool in organic chemistry, allowing alternative strategies towards synthetically useful scaffolds.1,2 In these systems, photoactive complexes, such as ruthenium or iridium, or organic dyes are employed to initiate organic reactions.3 Recently, a dinucelar gold complex was established as a highly effective photocatalyst.4-7 Utilizing this complex, Hashmi et al. developed new photoredox methods activating sp2 C-H bonds for elegant cross-couplings (Scheme 1). 6-7 The reactions proceed under very mild conditions and show a broad functional group tolerance.
Scheme 1. Gold-catalyzed photoredox reactions using a dinuclear gold complex.
The latest applications of novel photoredox catalytic systems using dinuclear gold complexes will be presented.
References
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- Xie, T. Zhang, F. Chen, N. Mehrkens, F. Rominger, M. Rudolph, A. S. K. Hashmi, Angew. Chem. Int. Ed. 2016, 55, 2934
Corresponding author email: sina.witzel@oci.uni-heidelberg.de