Rafael GRAMAGE-DORIA

Ruthenium-based catalytic systems are particularly appealing from an economic point of view with respect to other noble metals such as Pd, Rh, Ir, etc. In addition, ruthenium catalysts enable similar, not to mention, new reactions that cannot be tackled with other noble metals. In this respect, I will present our last efforts regarding ruthenium catalysts enabling C-H bond functionalization reactions to become compatible with industrially relevant oxidations and hydrogenations. I will also present how cyclic imides and amides turned out to be interesting weak directing groups for carbon-carbon and carbon-oxygen bond formations via Ru-catalyzed C-H bond functionalization strategies. Finally, I will show how it is possible to form amides from phthalimides in a single-step reaction without the need to form primary amines as intermediates.

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Wed. April 3 | 9.50am-10.30am – Ruthenium Catalysis: C-H Bond Functionalization and Beyond